Grid Portal Interface for Interactive Use and Monitoring of High-Throughput Proteome Annotation

High-throughput proteome annotation refers to the activity of extracting information from all proteins in a particular organism using bioinformatics software on a high performance computing platform such as the grid. The Encyclopedia of Life (EOL) project [1] aims to catalog all proteins in all species for public benefits using an Integrative Genome Annotation Pipeline [2] (iGAP). The intrinsic complexity of the pipeline makes iGAP an ideal life sciences application to drive grid software development. It is a flagship application for the TeraGrid project [3]. The deployment of iGAP on the grid using grid middleware and mediator software has been described previously [4]. The heterogeneous and distributed computing environment on the grid requires an interactive user interface where jobs may be submitted and monitored. Here we describe our international collaborative effort in creating a grid To whom correspondence should be addressed. Phone 858-822-1079, Fax 858-8224767 pp. 53–67, 2005. c © Springer-Verlag Berlin Heidelberg 2005 A. Konagaya and K. Satou (Eds.): LSGRID 2004, LNBI 3370,